Home › Grants › United States › Preclinical Proof of Concept Studies for Rare Diseases (R21 Clinical T
Preclinical Proof of Concept Studies for Rare Diseases (R21 Clinical Trial Not Allowed)
This notice of funding opportunity (NOFO) provides funding to conduct efficacy studies in an established rare disease preclinical model to demonstrate that a proposed therapeutic agent warrants further development.
Grant (non-repayable) Open now
- Funder
- National Institutes of Health
Funder profile and all of its programs - Amount
- Award amounts are not published in the listing; see the official page.
- Where
- United States (federal)
- Eligibility
- Open to businesses, self-employed people, nonprofits, colleges, universities, schools or research institutions and state, provincial, local or tribal governments. No cost sharing is required.
- Sectors
- Health and life sciences, Nonprofits and charities, Research and science
- Deadline
- Closes 2 July 2027
- Source
- Grants.gov XML extract (RFA-TR-25-002)
- Last checked
- 2 November 2026
- Funder contacts
- Public organizational contacts on file Unlock full profile / Sign up
From official open data: listed in the official Grants.gov extract on 2026-11-02. The summary is from the official listing; the eligibility line is our plain-language reading of its eligibility codes. Confirm details on the official page.
Related grant lists
Health and life sciences Nonprofits and charities Research and science Governments and public bodies Schools, colleges and research institutions Nonprofits and charities United States United States (national) Federal agency July 2027
Full eligibility results and funder contacts come with Pro and Lifetime, coming soon.
Information only. GrantSift is not affiliated with any funder. A match means a program is likely eligible or worth checking, not that you will be funded. Always confirm details on the official page. Applying through official portals is free.